Il2rg<tm1.1Flv> Targeted Allele Detail MGI Mouse (MGI:4887837)

Il2rg^tm1.1Flv
Targeted Allele Detail

Summary

Symbol:	Il2rg^tm1.1Flv
Name:	interleukin 2 receptor, gamma chain; targeted mutation 1.1, Richard A Flavell
MGI ID:	MGI:4887837
Gene:	Il2rg Location: ChrX:100307991-100311861 bp, - strand Genetic Position: ChrX, 43.9 cM
Alliance:	Il2rg^tm1.1Flv page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:168303
Parent Cell Line:	V17 (ES Cell)
Strain of Origin:	BALB/cAnNTac x 129S4/SvJae

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutation:		Insertion
		Mutation details: A floxed human ubiquitin promoter-driven hygromycin cassette replaced the coding region. Cre-mediated recombination removed the hygro cassette. (J:168303)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 6 strains available Cell Lines: 0 lines available
Carrying any Il2rg Mutation:	178 strains or lines available

Notes

Originally generated in conjunction with Rag2^tm1.1Flv.

References

Original:	J:168303 Song J, et al., A mouse model for the human pathogen Salmonella typhi. Cell Host Microbe. 2010 Oct 21;8(4):369-76
All:	90 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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