About   Help   FAQ
Tg(Vav1-cre)8Cgp
Transgene Detail
Summary
Symbol: Tg(Vav1-cre)8Cgp
Name: transgene insertion 8, Cristin G Print
MGI ID: MGI:4888391
Synonyms: vavCre8, VC8
Transgene: Tg(Vav1-cre)8Cgp  Location: unknown  
Alliance: Tg(Vav1-cre)8Cgp page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Vav1-cre)8Cgp expression driven by 1 gene
 
Mutation details: An SV40 intron, cre recombinase cDNA and an SV40 polyA cassette were inserted into a vector behind the Vav1 promoter. The construct was injected into pronuclei to generate transgenic mice. 2 lines, 1 and 8, resulted and both exhibited recombination in the majority of hematopoietic and endothelial cells but very little in other somatic cells. (J:81647)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Vav1 (species not specified)
Summary of all recombinase alleles driven by Vav1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:81647 Georgiades P, et al., vavCre Transgenic mice: A tool for mutagenesis in hematopoietic and endothelial lineages. Genesis. 2002 Dec;34(4):251-6
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory