Tg(MAR-Trpv5-cre)#Prae
Transgene Detail
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| Symbol: |
Tg(MAR-Trpv5-cre)#Prae |
| Name: |
transgene insertion, Jeppe Praetorius |
| MGI ID: |
MGI:4888728 |
| Synonyms: |
MAR-TRPV5-Cre |
| Transgene: |
Tg(MAR-Trpv5-cre)#Prae Location: unknown
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| Alliance: |
Tg(MAR-Trpv5-cre)#Prae page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(MAR-Trpv5-cre)#Prae expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Trpv5 |
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Mutation details: The transgenic construct consisted of a 3.6 kb fragment of the Trpv5 promoter inserted upstream of the cre recombinase coding region. This construct was insulated by a chicken lysozyme 5' matrix attachment region inserted in front of the Trpv5 promoter. Mice were generated by injecting the construct into male pronuclei of B6D2F2 zygotes. Founder line information was not available. Transgenic mice were validated by PCR and immunoblotting with a cre antibody. Recombinase activity was assessed in offspring from crosses of cre transgenics with a floxed Aqp2 line.
(J:168534)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Trpv5
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:168534 Hofmeister MV, et al., The TRPV5 Promoter as a Tool for Generation of Transgenic Mouse Models. Adv Exp Med Biol. 2011;704:277-86 |
| All: |
1 reference(s) |
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Analysis Tools
