Tg(Tert-cre/ERT2)1Brlt
Transgene Detail
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| Symbol: |
Tg(Tert-cre/ERT2)1Brlt |
| Name: |
transgene insertion 1, David T Breault |
| MGI ID: |
MGI:4941319 |
| Synonyms: |
mTert-CreER |
| Transgene: |
Tg(Tert-cre/ERT2)1Brlt Location: unknown
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| Alliance: |
Tg(Tert-cre/ERT2)1Brlt page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:169012
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| Parent Cell Line: |
J1 (ES Cell)
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| Strain of Origin: |
129S4/SvJae
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Tert-cre/ERT2)1Brlt expression driven by
1 gene
Transgene expression driven by:
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Mutation details: A cre/ERT2 cassette was cloned into a vector containing 4.4 kb of the murine Tert promoter. The linearized construct was electroporated into J1 ES cells for integration. 3 clones were selected for blastocyst injection and three chimeras were generated. One line containing 10 copies of the transgene was selected for further analysis.
(J:169012)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Tert
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:169012 Montgomery RK, et al., Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):179-84 |
| All: |
1 reference(s) |
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Analysis Tools
