Tg(Nes-cre/ERT2)#Kag
Transgene Detail
|
|
| Symbol: |
Tg(Nes-cre/ERT2)#Kag |
| Name: |
transgene insertion, Ryoichiro Kageyama |
| MGI ID: |
MGI:4941327 |
| Synonyms: |
Nestin-CreERT2 |
| Transgene: |
Tg(Nes-cre/ERT2)#Kag Location: unknown
|
| Alliance: |
Tg(Nes-cre/ERT2)#Kag page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inducible, Recombinase) |
| Inducer: |
|
tamoxifen |
| Mutation: |
|
Insertion
|
| |
|
Tg(Nes-cre/ERT2)#Kag expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| rat |
Nes (25491) |
|
|
|
| |
|
Mutation details: This transgene consists of a 5.8 kb fragment of the rat Nes promoter and a 1.8 kb fragment of the second intron of Nes driving expression of a tamoxifen-inducible form of cre recombinase followed by an SV40 poly A sequence. Three lines were created (lines 1, 4, and 5-1) with differing levels of activity (high, medium, and low, respectively) and leakiness (high, low and none, respectively). The pound symbol (#) is used to indicate that no line was specified or that lines were pooled.
(J:110145)
|
|
|
|
Activity: |
 Tissue activity of this recombinase allele
|
|
Driver:
|
Nes
(rat)
|
| |
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:169319 Muraguchi T, et al., NKX2.2 suppresses self-renewal of glioma-initiating cells. Cancer Res. 2011 Feb 1;71(3):1135-45 |
| All: |
42 reference(s) |
|
Analysis Tools
