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Selenoktm1.2Itl
Targeted Allele Detail
Summary
Symbol: Selenoktm1.2Itl
Name: selenoprotein K; targeted mutation 1.2, inGenious Targeting Laboratory
MGI ID: MGI:4941878
Synonyms: Selktm1.2Igl
Gene: Selenok  Location: Chr14:29690337-29697031 bp, + strand  Genetic Position: Chr14, 18.36 cM
Alliance: Selenoktm1.2Itl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:169169
Parent Cell Line:  iTL IC1 (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Cre-mediated recombination removed exons 2 and 3. (J:169169)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Selenok Mutation:  15 strains or lines available
References
Original:  J:169169 Verma S, et al., Selenoprotein K knockout mice exhibit deficient calcium flux in immune cells and impaired immune responses. J Immunol. 2011 Feb 15;186(4):2127-37
All:  7 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory