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Tg(Grm2-cre,-EGFP)631Lfr
Transgene Detail
Summary
Symbol: Tg(Grm2-cre,-EGFP)631Lfr
Name: transgene insertion 631, Louis F Reichardt
MGI ID: MGI:4943473
Synonyms: mGluR2::Cre
Transgene: Tg(Grm2-cre,-EGFP)631Lfr  Location: unknown  
Alliance: Tg(Grm2-cre,-EGFP)631Lfr page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Grm2-cre,-EGFP)631Lfr expression driven by 1 gene
 
Mutation detailsCre recombinase with a nuclear localization signal followed by an IRES-EGFP sequence was cloned into a plasmid vector containing 18 kb of 5' upstream Gria2 sequence including the first two exons. The excised expression cassette injected into mouse pronuclei to generate transgenic animals. (J:169866)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Grm2 (species not specified)
Summary of all recombinase alleles driven by Grm2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:169866 Chen AI, et al., TrkB (Tropomyosin-Related Kinase B) Controls the Assembly and Maintenance of GABAergic Synapses in the Cerebellar Cortex. J Neurosci. 2011 Feb 23;31(8):2769-80
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory