Et(icre)21733Rdav
Transgene Detail
|
|
| Symbol: |
Et(icre)21733Rdav |
| Name: |
enhancer trap 21733, Ron Davis |
| MGI ID: |
MGI:4947554 |
| Transgene: |
Et(icre)21733Rdav Location: unknown
|
| Alliance: |
Et(icre)21733Rdav page
|
|
| Strain of Origin: |
C57BL/6J
|
| Project Collection: |
Neuroscience Blueprint cre
|
|
| Transgene Type: |
|
Transgenic (Recombinase) |
| Mutation: |
|
Insertion
|
| |
|
Et(icre)21733Rdav expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Et(icre)21733Rdav (MGI:4947593) |
|
|
| |
|
Mutation details: An enhancer trap transgenic approach was used to generate these mice. The Itpka-icre transgene was designed with a 200 bp minimal promoter from the mouse Itpka (inositol 1,4,5-trisphosphate 3-kinase A) locus, a codon-improved cre recombinase (icre; improved with mammalian codon usage, no putative cryptic splice sites, altered stop codon, and reduced CpG content to limit the chances of epigenetic silencing in mammals), and an SV40 late polyA signal. This transgene was injected into C57BL/6J mouse embryos. Founders were crossed to C57BL/6 animals. Animals were crossed to B6-Gt(ROSA)26Sortm1Sor mice to assess cre activity/transmission. Cre positive, lacZ negative mice were subsequently bred to C57BL/6 mice to establish the 21733 line.
(J:150856)
|
|
|
|
Activity: |
 Tissue activity of this recombinase allele
|
|
Driver:
|
Et(icre)21733Rdav
(mouse)
|
| |
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
| Original: |
J:150856 Davis R, Large-scale enhancer trap project to generate transgenic cre alleles by Ron Davis at Baylor University. MGI Direct Data Submission. 2009; |
| All: |
1 reference(s) |
|
Analysis Tools
