Tg(SYN1-icre/mRFP1)9934Rdav
Transgene Detail
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| Symbol: |
Tg(SYN1-icre/mRFP1)9934Rdav |
| Name: |
transgene insertion 9934, Ron Davis |
| MGI ID: |
MGI:4947576 |
| Transgene: |
Tg(SYN1-icre/mRFP1)9934Rdav Location: unknown
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| Alliance: |
Tg(SYN1-icre/mRFP1)9934Rdav page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(SYN1-icre/mRFP1)9934Rdav expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| human |
SYN1 (6853) |
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Mutation details: A lentiviral transgenic approach was used to generate these mice. The synapsin-iCre-RFP lentiviral transgene was designed with a 450 bp human synapsin I promoter, codon-improved cre/monomeric red fluorescent protein fusion protein (icre/mRFP1), and woodchuck hepatitis virus post-transcriptional regulatory element (WPRE; to enhance the mRNA transcript stability). This packaged lentivirus was injected subzonally (under the zona pellucida) into 1-2 cell stage C57BL/6J mouse embryos. Founders were crossed to C57BL/6 animals. Animals were crossed to B6-Gt(ROSA)26Sortm1Sor mice to assess cre activity/transmission. Cre positive, lacZ negative mice were subsequently bred to C57BL/6 mice to create the 9934 line.
(J:150856)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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SYN1
(human)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:150856 Davis R, Large-scale enhancer trap project to generate transgenic cre alleles by Ron Davis at Baylor University. MGI Direct Data Submission. 2009; |
| All: |
4 reference(s) |
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Analysis Tools
