Slc19a3<tm1Said> Targeted Allele Detail MGI Mouse (MGI:4948864)

Slc19a3^tm1Said
Targeted Allele Detail

Summary

Symbol:	Slc19a3^tm1Said
Name:	solute carrier family 19, member 3; targeted mutation 1, Hamid M Said
MGI ID:	MGI:4948864
Synonyms:	Slc19a3^tm1Igl, Slc19a3^tm1Itl
Gene:	Slc19a3 Location: Chr1:82990244-83016169 bp, - strand Genetic Position: Chr1, 42.65 cM
Alliance:	Slc19a3^tm1Said page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:170952
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Mutation details: A neo cassette replaced exons 1 and 2. The absence of protein expression was confirmed by western blot analysis on intestine extracts. (J:170952)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Slc19a3 Mutation:	45 strains or lines available

References

Original:	J:170952 Reidling JC, et al., Impaired intestinal vitamin B1 (thiamin) uptake in thiamin transporter-2-deficient mice. Gastroenterology. 2010 May;138(5):1802-9
All:	3 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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