Grid2<tm1(cre)Mwa> Targeted Allele Detail MGI Mouse (MGI:4949272)

Grid2^tm1(cre)Mwa
Targeted Allele Detail

Summary

Symbol:	Grid2^tm1(cre)Mwa
Name:	glutamate receptor, ionotropic, delta 2; targeted mutation 1, Masahiko Watanabe
MGI ID:	MGI:4949272
Synonyms:	D2CreN, GluD2^Cre, Grid2^Cre
Gene:	Grid2 Location: Chr6:63232860-64681307 bp, + strand Genetic Position: Chr6, 29.77 cM
Alliance:	Grid2^tm1(cre)Mwa page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:170673
Parent Cell Line:	RENKA (ES Cell)
Strain of Origin:	C57BL/6N

Mutation
description

Allele Type:

Targeted (Null/knockout, Recombinase)

Mutation:

Insertion

Grid2^tm1(cre)Mwa expression driven by 1 gene

The cre sequence and an FRT-flanked neo cassette were inserted at the start codon. (J:170673)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Grid2 (mouse) Summary of all recombinase alleles driven by Grid2. Alliance mouse Grid2 gene page

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Grid2 Mutation:	85 strains or lines available

References

Original:	J:170673 Yamasaki M, et al., Glutamate receptor delta2 is essential for input pathway-dependent regulation of synaptic AMPAR contents in cerebellar Purkinje cells. J Neurosci. 2011 Mar 2;31(9):3362-74
All:	14 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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