Resp18<tm1Mlit> Targeted Allele Detail MGI Mouse (MGI:4949626)

Resp18^tm1Mlit
Targeted Allele Detail

Summary

Symbol:	Resp18^tm1Mlit
Name:	regulated endocrine-specific protein 18; targeted mutation 1, Jian Fei
MGI ID:	MGI:4949626
Gene:	Resp18 Location: Chr1:75248843-75255059 bp, - strand Genetic Position: Chr1, 38.65 cM
Alliance:	Resp18^tm1Mlit page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:171182
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Mutation details: The open reading frame was replaced by a neo cassette. A 50% reduction in protein expression was confirmed by western blot analysis on heterozygous brain extracts. (J:171182)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Resp18 Mutation:	17 strains or lines available

References

Original:	J:171182 Liang M, et al., Requirement of regulated endocrine-specific protein-18 for development and expression of regulated endocrine-specific protein-18 isoform c in mice. Mol Biol Rep. 2011 Apr;38(4):2557-62
All:	2 reference(s)

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