Cspg4tm1(cre)Akik
Targeted Allele Detail
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| Symbol: |
Cspg4tm1(cre)Akik |
| Name: |
chondroitin sulfate proteoglycan 4; targeted mutation 1, Akiko Nishiyama |
| MGI ID: |
MGI:4950067 |
| Synonyms: |
NG2CreKI, NG2 KO |
| Gene: |
Cspg4 Location: Chr9:56772388-56807154 bp, + strand Genetic Position: Chr9, 30.32 cM
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| Alliance: |
Cspg4tm1(cre)Akik page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:171287
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| Parent Cell Line: |
RENKA (ES Cell)
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| Strain of Origin: |
C57BL/6N
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| Allele Type: |
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Targeted (Null/knockout, Recombinase) |
| Mutations: |
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Insertion, Intragenic deletion
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Cspg4tm1(cre)Akik expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A targeting vector was designed so that it contained a homology arm-flanked nlsCre cDNA (nls;nuclear localization signal), a pgk-neo cassette 3' of the nlscre, and an MC1-driven diphtheria toxin selection gene. After homologous recombination in RENKA ES cells, targeted clones had the cre cDNA inserted immediately after the translational initiation codon of Cspg4. ES cell clones were injected into 8-cell CD1 embryos to produce germline chimeras to establish the knock-in line.
(J:171287)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Cspg4
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Cspg4 Mutation: |
101 strains or lines available
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| Original: |
J:171287 Hill RA, et al., NG2 cells are uniformly distributed and NG2 is not required for barrel formation in the somatosensory cortex. Mol Cell Neurosci. 2011 Apr;46(4):689-98 |
| All: |
2 reference(s) |
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Analysis Tools
