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Cul4atm1.1Pra
Targeted Allele Detail
Summary
Symbol: Cul4atm1.1Pra
Name: cullin 4A; targeted mutation 1.1, Pradip Raychaudhuri
MGI ID: MGI:5003269
Synonyms: Cul4A fl
Gene: Cul4a  Location: Chr8:13155623-13197940 bp, + strand  Genetic Position: Chr8, 5.73 cM
Alliance: Cul4atm1.1Pra page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:172043
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: Exons 4 through 8 were floxed. A floxed neo cassette used for selection was removed by cre-mediated recombination. (J:172043)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cul4a Mutation:  30 strains or lines available
References
Original:  J:172043 Kopanja D, et al., Proliferation defects and genome instability in cells lacking Cul4A. Oncogene. 2009 Jul 2;28(26):2456-65
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory