Ccbe1<tm1Lex> Targeted Allele Detail MGI Mouse (MGI:5007046)

Ccbe1^tm1Lex
Targeted Allele Detail

Summary

Symbol:	Ccbe1^tm1Lex
Name:	collagen and calcium binding EGF domains 1; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID:	MGI:5007046
Synonyms:	Ccbe1^lacZ
Gene:	Ccbe1 Location: Chr18:66189926-66424909 bp, - strand Genetic Position: Chr18, 39.13 cM, cytoband E1
Alliance:	Ccbe1^tm1Lex page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:171883
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Mutation details: This mutant allele was generated by homologous recombination in embryonic stem cells, with a lacZ cassette replacing the first and second coding exons of the gene. (J:171883, J:186594)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	42 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available Cell Lines: 0 lines available
Carrying any Ccbe1 Mutation:	19 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

Original:	J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All:	8 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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