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Cul9tm1.1Yxi
Targeted Allele Detail
Summary
Symbol: Cul9tm1.1Yxi
Name: cullin 9; targeted mutation 1.1, Yue Xiong
MGI ID: MGI:5007735
Synonyms: Cul9flox
Gene: Cul9  Location: Chr17:46811535-46857314 bp, - strand  Genetic Position: Chr17, 22.9 cM
Alliance: Cul9tm1.1Yxi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:170976
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 7. Flp-mediated recombination removed the neo cassette leaving exons 2 through 7 floxed. (J:170976)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cul9 Mutation:  110 strains or lines available
References
Original:  J:170976 Pei XH, et al., Cytoplasmic CUL9/PARC Ubiquitin Ligase Is a Tumor Suppressor and Promotes p53-Dependent Apoptosis. Cancer Res. 2011 Apr 15;71(8):2969-77
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory