About   Help   FAQ
Tg(Nppa-cre)m-3+4Vmc
Transgene Detail
Summary
Symbol: Tg(Nppa-cre)m-3+4Vmc
Name: transgene insertion m-3+4, Vincent M Christoffels
MGI ID: MGI:5013828
Synonyms: -3/+4mCre, NppaCre+
Transgene: Tg(Nppa-cre)m-3+4Vmc  Location: unknown  
Alliance: Tg(Nppa-cre)m-3+4Vmc page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Nppa-cre)m-3+4Vmc expression driven by 1 gene
 
Mutation detailsThe transgenic construct consists of a sequence fragment encoding a consensus Kozak signal, a nuclear localization signal and cre recombinase inserted at the start codon of the mouse Nppa genomic sequence (-3 to +4 kb relative to the transcription start site). The 0.7 kb proximal regulatory region, containing the promoter and silencer and enhancer sequences, is included, as is the NRSE (neuron-restrictive silencer element) in the 3' UTR. (J:86158)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nppa (mouse)
Summary of all recombinase alleles driven by Nppa.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:86158 de Lange FJ, et al., Atrial cardiomyocyte-specific expression of Cre recombinase driven by an Nppa gene fragment. Genesis. 2003 Sep;37(1):1-4
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory