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Cux2tm1.1(cre)Mull
Targeted Allele Detail
Summary
Symbol: Cux2tm1.1(cre)Mull
Name: cut-like homeobox 2; targeted mutation 1.1, Ulrich Mueller
MGI ID: MGI:5014209
Synonyms: Cux2-IRES-Cre
Gene: Cux2  Location: Chr5:121996025-122188522 bp, - strand  Genetic Position: Chr5, 62.02 cM
Alliance: Cux2tm1.1(cre)Mull page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:151755
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Project Collection: Neuroscience Blueprint cre
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Cux2tm1.1(cre)Mull expression driven by 1 gene
 
Mutation details: A targeting vector was designed to insert an internal ribosomal entry site, nuclear-localized Cre recombinase gene, and polyA signal (IRES-Cre-pA) followed by an FRT-flanked PGK-Neo cassette into the 3' untranslated region of the cut-like homeobox 2 (Cux2) locus. Flp-mediated recombination removed the FRT-flanked PGK-Neo cassette. (J:151755)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cux2 (mouse)
Summary of all recombinase alleles driven by Cux2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 68 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cux2 Mutation:  43 strains or lines available
References
Original:  J:151755 NIH Neuroscience Blueprint Cre Driver Network, Cre recombinase-expressing mice generated for the NIH Neuroscience Blueprint Cre Driver Network. MGI Direct Data Submission. 2009;
All:  14 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory