Tg(Slc6a3-icre/ERT2)2Gloss
Transgene Detail
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| Symbol: |
Tg(Slc6a3-icre/ERT2)2Gloss |
| Name: |
transgene insertion 2, Bernd Gloss |
| MGI ID: |
MGI:5049906 |
| Synonyms: |
DAT-iCreER |
| Transgene: |
Tg(Slc6a3-icre/ERT2)2Gloss Location: unknown
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| Alliance: |
Tg(Slc6a3-icre/ERT2)2Gloss page
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Slc6a3-icre/ERT2)2Gloss expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Slc6a3 (MGI:94862) |
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Mutation details: The mouse bacterial artificial chromosome (BAC) RP23-408F13 containing Slc6a3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, gene, was modified by insertion of sequence encoding iCreER at the Slc6a3 translation initiation ATG, and addition of a Kozak sequence upstream of the ATG. This BAC also contains the following genes: Clptm1l (CLPTM1-like), Tert (telomerase reverse transcriptase), and Slc6a18 (solute carrier family 6 (neurotransmitter transporter), member 18). The modified BAC was used to generate the DAT-iCreER transgene, which was microinjected into C57BL/6NTac fertilized eggs. Founder line 2 was subsequently established.
(J:173676)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Slc6a3
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:173676 Gloss B, Generation of an inducible Slc6a3 cre transgene. MGI Direct Data Submission. 2011; |
| All: |
7 reference(s) |
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Analysis Tools
