Ptgdstm1.1(cre)Gvn
Targeted Allele Detail
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| Symbol: |
Ptgdstm1.1(cre)Gvn |
| Name: |
prostaglandin D2 synthase (brain); targeted mutation 1.1, Marco Giovannini |
| MGI ID: |
MGI:5051626 |
| Synonyms: |
PGDSCre |
| Gene: |
Ptgds Location: Chr2:25356721-25360058 bp, - strand Genetic Position: Chr2, 17.28 cM
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| Alliance: |
Ptgdstm1.1(cre)Gvn page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:173718
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Recombinase) |
| Mutations: |
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Insertion, Intragenic deletion
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Ptgdstm1.1(cre)Gvn expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Ptgds (MGI:99261) |
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Mutation details: A targeting vector was constructed with the nls-cre recombinase sequence fused to exon 1 of the Ptgds locus and a poly A signal with a floxed EGFP-hygromycin selection cassette 3' to the cre poly A signal. Homologous recombination in ES cells was performed to replace exon 1 with the targeting construct. Chimeras were crossed with FVB/N mice. The floxed selection cassette was excised by crossing offspring to the Tg(EIIa-cre)C5379Lmgd deletor line and the EIIa transgene was bred from the background.
(J:173718)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Ptgds
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Ptgds Mutation: |
17 strains or lines available
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| Original: |
J:173718 Kalamarides M, et al., Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes. Oncogene. 2011 May 19;30(20):2333-44 |
| All: |
3 reference(s) |
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Analysis Tools
