About   Help   FAQ
Sfrp4tm1.1Blan
Targeted Allele Detail
Summary
Symbol: Sfrp4tm1.1Blan
Name: secreted frizzled-related protein 4; targeted mutation 1.1, Beate Lanske
MGI ID: MGI:5052054
Gene: Sfrp4  Location: Chr13:19807345-19816995 bp, + strand  Genetic Position: Chr13, 6.99 cM
Alliance: Sfrp4tm1.1Blan page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:173962
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation details: A loxP site was inserted 5' of the translation initiation site in exon 1 and a floxed neo cassette was inserted downstream of exon 1. Cre-mediated recombination removed exon 1. (J:173962)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sfrp4 Mutation:  18 strains or lines available
References
Original:  J:173962 Christov M, et al., Genetic ablation of sfrp4 in mice does not affect serum phosphate homeostasis. Endocrinology. 2011 May;152(5):2031-6
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory