Gt(ROSA)26Sortm1Dwir
Targeted Allele Detail
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| Symbol: |
Gt(ROSA)26Sortm1Dwir |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Dagmar Wirth |
| MGI ID: |
MGI:5056481 |
| Synonyms: |
ROSALUC |
| Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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| Alliance: |
Gt(ROSA)26Sortm1Dwir page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:173806
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| Parent Cell Line: |
IB10/E14IB10 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: A construct, which contained (5' to 3') an adenoviral splice acceptor site (SA); a wild-type FRT site, a floxed inverted luciferase cassette; a puromycin N-acetyltransferase (PAC) gene; a non-integrating FRT site; and a promoter and start-codon deficient neomycin phosphotransferase gene, was inserted into the locus. This allele is suitable for RMCE to replace the inverted luciferase gene with a gene of interest.
(J:173806)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gt(ROSA)26Sor Mutation: |
994 strains or lines available
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| Original: |
J:173806 Sandhu U, et al., Strict control of transgene expression in a mouse model for sensitive biological applications based on RMCE compatible ES cells. Nucleic Acids Res. 2011 Jan 1;39(1):e1 |
| All: |
1 reference(s) |
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Analysis Tools
