Tg(Rxfp2-cre)#Aia
Transgene Detail
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| Symbol: |
Tg(Rxfp2-cre)#Aia |
| Name: |
transgene insertion, Alexander I Agoulnik |
| MGI ID: |
MGI:5141475 |
| Synonyms: |
Rxfp2-icre |
| Transgene: |
Tg(Rxfp2-cre)#Aia Location: unknown
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| Alliance: |
Tg(Rxfp2-cre)#Aia page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Rxfp2-cre)#Aia expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Rxfp2 |
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Mutation details: The transgene comprises the 2429 base pairs that reside immediately upstream of the translation initiation codon of the relaxin/insulin-like family peptide receptor 2 gene, a 1.1-kb DNA fragment containing a consensus Kozak sequence, and coding sequences for the nuclear localization signal of the SV40 large T antigen and for improved Cre recombinase (iCre). Examination of X-gal-stained tissues from male mice bearing both this and the Cre-reporter transgene Gt(ROSA)26tm1Sor demonstrate Cre expression in the testis, epididymis and cremaster muscle of the adult and in the developing testis, epididymis and gubernacular ligaments at embryonic day 14 (E14). RT-PCR analysis of male embryonic tissues confirmed this expression, though only weakly in the vas deferens. Lines 1 and 5 were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:122478)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Rxfp2
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:174719 Li Z, et al., Uterine cysts in female mice deficient for caveolin-1 and insulin-like 3 receptor RXFP2. Endocrinology. 2011 Jun;152(6):2474-82 |
| All: |
2 reference(s) |
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Analysis Tools
