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Tg(Pdgfrb-cre)35Vli
Transgene Detail
Summary
Symbol: Tg(Pdgfrb-cre)35Vli
Name: transgene insertion 35, Volkhard Lindner
MGI ID: MGI:5291826
Synonyms: PDGFRB-Cre(VL), Pdgfrbeta-Cre, Tg(Pdgfrb-cre)35Vli, Tg(Pdgfrb-Cre)45Vli
Transgene: Tg(Pdgfrb-cre)35Vli  Location: unknown  
Alliance: Tg(Pdgfrb-cre)35Vli page
Transgene
origin
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Pdgfrb-cre)35Vli expression driven by 1 gene
 
Mutation details: The transgenic construct contained a 4.8 kb fragment of Pdgfrb including the promoter and the first exon fused to a nuclear-targeted cre recombinase sequence. The construct was injected into fertilized oocytes. Founders were crossed to Gt(ROSA)26Sortm1Sor reporter mice to analyze cre activity in embryonic and adult tissues. Line 35 was used for further experiments. (J:175492)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pdgfrb (species not specified)
Summary of all recombinase alleles driven by Pdgfrb.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:175492 Cuttler AS, et al., Characterization of Pdgfrb-Cre transgenic mice reveals reduction of ROSA26 reporter activity in remodeling arteries. Genesis. 2011 Aug;49(8):673-80
All:  27 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory