Shhtm1(cre/ERT2)Tshim
Targeted Allele Detail
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| Symbol: |
Shhtm1(cre/ERT2)Tshim |
| Name: |
sonic hedgehog; targeted mutation 1, Tomomi Shimogori |
| MGI ID: |
MGI:5294343 |
| Synonyms: |
Shh-IRES-Cre |
| Gene: |
Shh Location: Chr5:28661838-28672099 bp, - strand Genetic Position: Chr5, 14.39 cM
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| Alliance: |
Shhtm1(cre/ERT2)Tshim page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:171106
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Shhtm1(cre/ERT2)Tshim expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Shh (MGI:98297) |
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Mutation details: Cre recombinase was inserted into the 3' end of the locus. All procedures for generating knock-in animals were performed at inGenious Targeting Laboratory (Stony Brook, NY). An internal ribosome entry site (IRES) preceding the cre coding sequence permitted expression of both Shh and cre proteins from the same mRNA. No disruption of endogenous gene activity was detected.
(J:171106)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Shh
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Shh Mutation: |
48 strains or lines available
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| Original: |
J:171106 Suzuki-Hirano A, et al., Dynamic spatiotemporal gene expression in embryonic mouse thalamus. J Comp Neurol. 2011 Feb 15;519(3):528-43 |
| All: |
1 reference(s) |
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Analysis Tools
