About   Help   FAQ
Cdh5tm1Dvst
Targeted Allele Detail
Summary
Symbol: Cdh5tm1Dvst
Name: cadherin 5; targeted mutation 1, Dietmar Vestweber
MGI ID: MGI:5294807
Gene: Cdh5  Location: Chr8:104828257-104871143 bp, + strand  Genetic Position: Chr8, 53.04 cM
Alliance: Cdh5tm1Dvst page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:189010
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change, RMCE-ready)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2. A neo cassette with a 3' lox2272 was inserted downstream of exon 2. (J:177191)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdh5 Mutation:  59 strains or lines available
Notes
References
Original:  J:177191 Schulte D, et al., Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability. EMBO J. 2011;30(20):4157-70
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory