Tg(Krt15-cre/ERT2)ANiem
Transgene Detail
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Symbol: |
Tg(Krt15-cre/ERT2)ANiem |
Name: |
transgene insertion A, Catherin Niemann |
MGI ID: |
MGI:5296247 |
Synonyms: |
A_K15CreERlow |
Transgene: |
Tg(Krt15-cre/ERT2)ANiem Location: unknown
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Alliance: |
Tg(Krt15-cre/ERT2)ANiem page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Krt15-cre/ERT2)ANiem expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Krt15 |
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Mutation details: A 5 kb Krt15 promoter fragment was inserted into a vector containing the cre/ERT2 (Cre/ER(G)T2) cassette. The construct was microinjected into oocytes and eight founder lines were obtained. 3 lines were found to exhibit specific cre nuclear staining patterns and recombined reporter patterns (in offspring of crosses) in hair follicles after tamoxifen administration. A low expressing line, line A, was established.
(J:175633)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Krt15
(species not specified)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:175633 Petersson M, et al., TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis. EMBO J. 2011;30(15):3004-18 |
All: |
2 reference(s) |
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