Tg(Krt15-cre/ERT2)CNiem
Transgene Detail
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| Symbol: |
Tg(Krt15-cre/ERT2)CNiem |
| Name: |
transgene insertion C, Catherin Niemann |
| MGI ID: |
MGI:5296325 |
| Synonyms: |
C_K15CreERhigh |
| Transgene: |
Tg(Krt15-cre/ERT2)CNiem Location: unknown
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| Alliance: |
Tg(Krt15-cre/ERT2)CNiem page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Krt15-cre/ERT2)CNiem expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Krt15 |
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Mutation details: A 5 kb Krt15 promoter fragment was inserted into a vector containing the cre/ERT2 (Cre/ER(G)T2) cassette. The construct was microinjected into oocytes and eight founder lines were obtained. 3 lines were found to exhibit specific cre nuclear staining patterns and recombined reporter patterns (in offspring of crosses) in hair follicles after tamoxifen administration. A high expressing line, line C, was established.
(J:175633)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Krt15
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:175633 Petersson M, et al., TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis. EMBO J. 2011;30(15):3004-18 |
| All: |
2 reference(s) |
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Analysis Tools
