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Ntstm1(cre)Mgmj
Targeted Allele Detail
Summary
Symbol: Ntstm1(cre)Mgmj
Name: neurotensin; targeted mutation 1, Martin G Myers, Jr
MGI ID: MGI:5296932
Synonyms: NtsCre
Gene: Nts  Location: Chr10:102317617-102326294 bp, - strand  Genetic Position: Chr10, 53.56 cM, cytoband D1
Alliance: Ntstm1(cre)Mgmj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:176657
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Ntstm1(cre)Mgmj expression driven by 1 gene
 
Mutation details: An IRES-cre sequence was inserted into the 3' UTR of the Nts gene between the stop codon and the polyadenylation sequence. A floxed neo cassette was inserted downstream of the transcribed Nts sequence. (J:176657)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nts (mouse)
Summary of all recombinase alleles driven by Nts.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nts Mutation:  18 strains or lines available
References
Original:  J:176657 Leinninger GM, et al., Leptin Action via Neurotensin Neurons Controls Orexin, the Mesolimbic Dopamine System and Energy Balance. Cell Metab. 2011 Sep 7;14(3):313-23
All:  34 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory