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Tg(Plp1-cre)F633Rako
Transgene Detail
Summary
Symbol: Tg(Plp1-cre)F633Rako
Name: transgene insertion F633, Rashmi Kothary
MGI ID: MGI:5297401
Synonyms: Plp-Cre line F633
Transgene: Tg(Plp1-cre)F633Rako  Location: unknown  
Alliance: Tg(Plp1-cre)F633Rako page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Plp1-cre)F633Rako expression driven by 1 gene
 
Mutation detailsCre cDNA was inserted into a Plp1 promoter cassette consisting of exon 1 and intron 1 of the mouse Plp1 gene. The transgene construct was microinjected into 1-cell embryos. 6/29 founders were positive for the transgene and 2 showed successful germline transmission. RT-PCR indicated that Line F633 was expressed solely in the spinal cord, cerebellum, and cortex at P4 and P28. (J:172435)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Plp1 (mouse)
Summary of all recombinase alleles driven by Plp1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:172435 Michalski JP, et al., The Proteolipid Protein Promoter Drives Expression outside of the Oligodendrocyte Lineage during Embryonic and Early Postnatal Development. PLoS One. 2011;6(5):e19772
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory