Tg(Plp1-cre)F627Rako
Transgene Detail
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| Symbol: |
Tg(Plp1-cre)F627Rako |
| Name: |
transgene insertion F627, Rashmi Kothary |
| MGI ID: |
MGI:5297408 |
| Synonyms: |
Plp-Cre line F627 |
| Transgene: |
Tg(Plp1-cre)F627Rako Location: unknown
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| Alliance: |
Tg(Plp1-cre)F627Rako page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Plp1-cre)F627Rako expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Plp1 (MGI:97623) |
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Mutation details: Cre cDNA was inserted into a Plp1 promoter cassette consisting of exon 1 and intron 1 of the mouse Plp1 gene. The transgene construct was microinjected into 1-cell embryos. 6/29 founders were positive for the transgene and 2 showed successful germline transmission. Lines F627 showed a wider expression pattern at P4 by RT-PCR with transcripts detected in spinal cord, cerebellum, and cortex and additionally in liver, kidney and tibialis anterior muscle. At P28, only CNS expression was detected.
(J:172435)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Plp1
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:172435 Michalski JP, et al., The Proteolipid Protein Promoter Drives Expression outside of the Oligodendrocyte Lineage during Embryonic and Early Postnatal Development. PLoS One. 2011;6(5):e19772 |
| All: |
1 reference(s) |
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Analysis Tools
