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Tg(Lhx2-cre)1Lcar
Transgene Detail
Summary
Symbol: Tg(Lhx2-cre)1Lcar
Name: transgene insertion 1, Leif Carlsson
MGI ID: MGI:5300954
Synonyms: Lhx2-Cre
Transgene: Tg(Lhx2-cre)1Lcar  Location: unknown  
Alliance: Tg(Lhx2-cre)1Lcar page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Lhx2-cre)1Lcar expression driven by 1 gene
 
Mutation detailsThe transgenic construct was composed of an 11 kb fragment of the Lhx2 promoter which also contained the first 36 bp of the coding sequence, fused in-frame with cre cDNA. An SV40 polyadenylation sequence was added. Two founder lines were obtained upon pronuclear injection of the construct. One of the founder lines was chosen for further analysis. (J:176341)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lhx2 (species not specified)
Summary of all recombinase alleles driven by Lhx2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:176341 Hagglund AC, et al., Lhx2 is required for patterning and expansion of a distinct progenitor cell population committed to eye development. PLoS One. 2011;6(8):e23387
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory