Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(Nes-cre/ERT2,-ALPP)1Sbk
Name:	transgene insertion 1, Suzanne J Baker
MGI ID:	MGI:5304277
Synonyms:	Nes-CreERT2-IRES-hPLAP, Nestin-CreERT2
Transgene:	Tg(Nes-cre/ERT2,-ALPP)1Sbk  Location: unknown
Alliance:	Tg(Nes-cre/ERT2,-ALPP)1Sbk page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Tg(Nes-cre/ERT2,-ALPP)1Sbk expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Nes   Mutation details: The nestin promoter and second intron enhancer control cre recombinase followed by an IRES-human placental alkaline phosphatase (IRES-hPLAP, official symbol ALPP) sequence. Further information regarding the transgene is not currently available. (J:148343)

Activity:	Tissue activity of this recombinase allele
Driver:	Nes (species not specified) Summary of all recombinase alleles driven by Nes.

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Tg(Nes-cre/ERT2,-ALPP)1Sbk

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:148343 Cicero SA, et al., Cells previously identified as retinal stem cells are pigmented ciliary epithelial cells. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6685-90
All:	14 reference(s)