Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | Notes | References

Symbol:	Is(14)5Rdf
Name:	insertion, Chr 14, Riccardo Dalla-Favera 5
MGI ID:	MGI:5304347
Synonyms:	Is5Rdf
Gene:	Is(14)5Rdf  Location: unknown  Genetic Position: Chr14, Syntenic

Germline Transmission:	Earliest citation of germline transmission: J:179879
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted Mutation:    Insertion   Mutation details: The targeting vector contained a PGK-Hygro cassette, loxP and FRT sites, inserted in the telomeric region of 14qC3, approximately 2 kb centromeric to the last exon of Rnaseh2b gene.

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Is(14)5Rdf

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Is(14)5Rdf Mutation:	1 strain or line available

Original:	J:179879 Lia M, et al., Functional dissection of the chromosome 13q14 tumor-suppressor locus using transgenic mouse lines. Blood. 2012 Mar 29;119(13):2981-90
All:	1 reference(s)