Ppm1atm1Xya
Targeted Allele Detail
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| Symbol: |
Ppm1atm1Xya |
| Name: |
protein phosphatase 1A, magnesium dependent, alpha isoform; targeted mutation 1, Xiao Yang |
| MGI ID: |
MGI:5304768 |
| Synonyms: |
Ppm1afl |
| Gene: |
Ppm1a Location: Chr12:72804231-72846593 bp, + strand Genetic Position: Chr12, 30.26 cM, cytoband C3
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| Alliance: |
Ppm1atm1Xya page
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Delayed re-epithelialization during wound healing in Ppm1atm1Xya/Ppm1atm1Xya Tg(KRT5-cre)1Xya/0 mice
Show the 1 phenotype image(s) involving this allele.
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| Germline Transmission: |
Earliest citation of germline transmission:
J:178733
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| Parent Cell Line: |
TC1/TC-1 (ES Cell)
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| Strain of Origin: |
129S6/SvEvTac
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 3.
(J:178733)
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Generation of the Ppm1atm1Xya and Ppm1atm1.1Xya alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Ppm1a Mutation: |
23 strains or lines available
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| Original: |
J:178733 Yang X, et al., Delayed Re-epithelialization in Ppm1a Gene-deficient Mice Is Mediated by Enhanced Activation of Smad2. J Biol Chem. 2011 Dec 9;286(49):42267-73 |
| All: |
1 reference(s) |
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Analysis Tools
