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Tn(sb-SBlac)C.176599bFsp
Transgene Detail
Summary
Symbol: Tn(sb-SBlac)C.176599bFsp
Name: transposon insertion C.176599b, Francois Spitz
MGI ID: MGI:5305460
Synonyms: HoxDTpSB1, SB176599b
Transgene: Tn(sb-SBlac)C.176599bFsp  Location: unknown  Genetic Position: Chr2, Syntenic
Alliance: Tn(sb-SBlac)C.176599bFsp page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Transposon induced (Conditional ready, Reporter)
Mutation:    Transposon insertion
 
Mutation detailsMobilization of the transposon from TgTn(sb-SBlac)CFsp transgenic mice with Sleeping Beauty transposase from an unidentified line of TgTn(sb-SBlac)15Fsp transgenic mice results in the integration of the transposon at chr2:73958058-73958059 (GRCm39) in reverse (tel-cen) orientation. This location is in the gene desert between Atp5g3 and Lnp. The transposon consists of a Sleeping Beauty transposon inverted repeat, loxP site, human beta-globin HBB minimal promoter, the lacZ beta-galactosidase reporter gene, SV40 poly(A) signal sequence, and a Sleeping Beauty transposon direct repeat. LacZ expression is detected in the distal limbs and genital bud of E11.5 embryos. (J:180121)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:180121 Ruf S, et al., Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor. Nat Genet. 2011 Apr;43(4):379-86
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory