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Csf1tm1.1Sabw
Targeted Allele Detail
Summary
Symbol: Csf1tm1.1Sabw
Name: colony stimulating factor 1 (macrophage); targeted mutation 1.1, Sherry Abboud Werner
MGI ID: MGI:5305689
Synonyms: CSF-1flox
Gene: Csf1  Location: Chr3:107648364-107667785 bp, - strand  
Alliance: Csf1tm1.1Sabw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:180199
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream od exon 4. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the neo cassette and left exons 4 through 6 floxed. (J:180199)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csf1 Mutation:  48 strains or lines available
References
Original:  J:180199 Harris SE, et al., Meox2Cre-mediated disruption of CSF-1 leads to osteopetrosis and osteocyte defects. Bone. 2012 Jan;50(1):42-53
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory