Tg(Acta2-cre/ERT2)#Pcn Transgene Detail MGI Mouse (MGI:5305721)

Tg(Acta2-cre/ERT2)#Pcn
Transgene Detail

Summary

Symbol:	Tg(Acta2-cre/ERT2)#Pcn
Name:	transgene insertion, Pierre Chambon
MGI ID:	MGI:5305721
Synonyms:	alphaSMA-Cre-ER^T2, Sma^CreER
Transgene:	Tg(Acta2-cre/ERT2)#Pcn Location: unknown
Alliance:	Tg(Acta2-cre/ERT2)#Pcn page

Transgene
origin

Strain of Origin:

FVB/N

Transgene
description

Transgene Type:

Transgenic (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Tg(Acta2-cre/ERT2)#Pcn expression driven by 1 gene

Mutation details: A construct containing cre fused to ERT2 followed by an frt flanked PGK-neo cassette was inserted at the initiation codon of Acta2 in a 175 kb mouse BAC. Tamoxifen-induced cre activity was seen in smooth muscle cells. (J:144642)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Acta2 (mouse) Summary of all recombinase alleles driven by Acta2. Comparative matrix view of recombinase activities Alliance mouse Acta2 gene page

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

Original:	J:144642 Wendling O, et al., Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse. Genesis. 2009 Jan;47(1):14-8
All:	70 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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