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Grin2ctm2(icre)Mwa
Targeted Allele Detail
Summary
Symbol: Grin2ctm2(icre)Mwa
Name: glutamate receptor, ionotropic, NMDA2C (epsilon 3); targeted mutation 2, Masahiko Watanabe
MGI ID: MGI:5306941
Synonyms: E3CreN, GluN2CiCre
Gene: Grin2c  Location: Chr11:115139995-115158069 bp, - strand  Genetic Position: Chr11, 80.8 cM
Alliance: Grin2ctm2(icre)Mwa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:180582
Parent Cell Line:  RENKA (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Grin2ctm2(icre)Mwa expression driven by 1 gene
 
Mutation details: A vector was constructed to insert an improved cre recombinase and an Frt-flanked neomycin cassette into the translation initiation site (in-frame) of the Grin2c gene by homologous recombination in RENKA ES cells. (J:180582)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Grin2c (mouse)
Summary of all recombinase alleles driven by Grin2c.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grin2c Mutation:  56 strains or lines available
References
Original:  J:180582 Miyazaki T, et al., Cav2.1 in Cerebellar Purkinje Cells Regulates Competitive Excitatory Synaptic Wiring, Cell Survival, and Cerebellar Biochemical Compartmentalization. J Neurosci. 2012 Jan 25;32(4):1311-1328
All:  9 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
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