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Neurod6tm2(cre/ERT2)Kan
Targeted Allele Detail
Summary
Symbol: Neurod6tm2(cre/ERT2)Kan
Name: neurogenic differentiation 6; targeted mutation 2, Klaus-Armin Nave
MGI ID: MGI:5308768
Synonyms: NCER-Neo, NEX-CreERT2
Gene: Neurod6  Location: Chr6:55654807-55658248 bp, - strand  Genetic Position: Chr6, 27.53 cM
Alliance: Neurod6tm2(cre/ERT2)Kan page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181084
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Neurod6tm2(cre/ERT2)Kan expression driven by 1 gene
 
Mutation details: A targeting vector was used to insert the cre/ERT2 cDNA with the SV40 polyA sequence and an Frt-neo-Frt cassette 3' to the cre sequence into exon 2, replacing the coding region of the Neurod6 gene. (J:181084)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Neurod6 (mouse)
Summary of all recombinase alleles driven by Neurod6.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Neurod6 Mutation:  18 strains or lines available
References
Original:  J:181084 Agarwal A, et al., In vivo imaging and noninvasive ablation of pyramidal neurons in adult NEX-CreERT2 mice. Cereb Cortex. 2012 Jul;22(7):1473-86
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory