Synbtm1.1Ics
Targeted Allele Detail
|
|
| Symbol: |
Synbtm1.1Ics |
| Name: |
syncytin b; targeted mutation 1.1, Mouse Clinical Institute |
| MGI ID: |
MGI:5308858 |
| Gene: |
Synb Location: Chr14:69526793-69531748 bp, - strand Genetic Position: Chr14, 36.04 cM
|
| Alliance: |
Synbtm1.1Ics page
|
|
| Germline Transmission: |
Earliest citation of germline transmission:
J:180242
|
| Parent Cell Line: |
Not Specified (ES Cell)
|
| Strain of Origin: |
129S2/SvPas
|
|
| Allele Type: |
|
Targeted (Conditional ready, No functional change) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: A loxP site was inserted upstream of the coding sequence. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of the coding region. Flp-mediated recombination removed the neo cassette and left the coding sequence floxed.
(J:180242)
|
|
Targeted disruption of the single exon Synb gene to generate the Synbtm1.1Ics and Synbtm1.2Ics alleles |
|
|
|
|
| Original: |
J:180242 Dupressoir A, et al., A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1164-73 |
| All: |
1 reference(s) |
|
Analysis Tools
