Nhlrc1<tm1.2Geno> Targeted Allele Detail MGI Mouse (MGI:5312925)

Nhlrc1^tm1.2Geno
Targeted Allele Detail

Summary

Symbol:	Nhlrc1^tm1.2Geno
Name:	NHL repeat containing 1; targeted mutation 1.2, Genoway
MGI ID:	MGI:5312925
Synonyms:	Epm2b^-
Gene:	Nhlrc1 Location: Chr13:47166033-47168326 bp, - strand Genetic Position: Chr13, 24.5 cM
Alliance:	Nhlrc1^tm1.2Geno page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:181559
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S2/SvPas

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Cre-mediated recombination removed the neo cassette and coding exon. (J:181559)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Nhlrc1 Mutation:	16 strains or lines available

References

Original:	J:181559 Criado O, et al., Lafora bodies and neurological defects in malin-deficient mice correlate with impaired autophagy. Hum Mol Genet. 2012 Apr 1;21(7):1521-33
All:	11 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24