Mirc19 MGI Mouse Complex/Cluster/Region Detail - MGI:5313574 - microRNA cluster 19, including Mir212 through Mir132

Mirc19 Complex/Cluster/Region Detail

Symbol

Mirc19
Name

microRNA cluster 19, including Mir212 through Mir132

Feature Type

complex/cluster/region
IDs

MGI:5313574
Cluster Members

Mir212, Mir132 (2 members)

Sequence Map

Chr11:75064214-75064573 bp
From MGI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, Syntenic

SNPs within 2kb

63 from dbSNP Build 142

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Phenotype Summary

15 phenotypes from 4 alleles in 3 genetic backgrounds
25 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

8
Targeted

8
Find Mice (IMSR)

0 strains or lines available

Mice homozygous for a knock-out allele exhibit disrupted cortical synaptic transmission and plasticity. Mice homozygous for another knock-out allele exhibit abnormal mammary gland development.

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miRBase

MI0000158, MI0000696

Summaries

All 26

Phenotypes 25
Earliest

J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
Latest

J:357960 Stojanovic T, et al., Age-Dependent and Pathway-Specific Bimodal Action of Nicotine on Synaptic Plasticity in the Hippocampus of Mice Lacking the miR-132/212 Genes. Cells. 2022 Jan 13;11(2)

Mirc19 Cluster contains:

More Data for these features

Member	Feature Type	Location
Mir212, microRNA 212	miRNA gene	Chr11:75064214-75064304 (+)
Mir132, microRNA 132	miRNA gene	Chr11:75064508-75064573 (+)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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