Lrp2tm2(EGFP/cre)Tew
Targeted Allele Detail
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| Symbol: |
Lrp2tm2(EGFP/cre)Tew |
| Name: |
low density lipoprotein receptor-related protein 2; targeted mutation 2, Thomas E Willnow |
| MGI ID: |
MGI:5314898 |
| Synonyms: |
Lrp2tmEGFP |
| Gene: |
Lrp2 Location: Chr2:69254679-69416373 bp, - strand Genetic Position: Chr2, 40.74 cM
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| Alliance: |
Lrp2tm2(EGFP/cre)Tew page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:181474
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Recombinase) |
| Mutations: |
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Insertion, Intragenic deletion
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Lrp2tm2(EGFP/cre)Tew expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Lrp2 (MGI:95794) |
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Mutation details: A minigene construct contained intron 1 of the rabbit beta-globin sequence followed by an EGFP/cre fusion gene with a nuclear localization signal and a translational stop codon. Homologous recombination in ES cells replaced exon 1 and 3.6 kb of intron 1 of the Lrp2 locus with the EGFP/cre minigene.
(J:181474)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Lrp2
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Lrp2 Mutation: |
261 strains or lines available
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| Original: |
J:181474 Christ A, et al., LRP2 Is an Auxiliary SHH Receptor Required to Condition the Forebrain Ventral Midline for Inductive Signals. Dev Cell. 2012 Feb 14;22(2):268-78 |
| All: |
1 reference(s) |
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Analysis Tools
