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Aicdatm1(cre)Njen
Targeted Allele Detail
Summary
Symbol: Aicdatm1(cre)Njen
Name: activation-induced cytidine deaminase; targeted mutation 1, Nancy A Jenkins
MGI ID: MGI:5314932
Synonyms: AicdaCre
Gene: Aicda  Location: Chr6:122530768-122541139 bp, + strand  Genetic Position: Chr6, 57.65 cM, cytoband F2
Alliance: Aicdatm1(cre)Njen page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181782
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Aicdatm1(cre)Njen expression driven by 1 gene
 
Mutation details: The cDNA encoding cre recombinase was inserted into Aicda between the stop codon and the 3' untranslated region. Details will be published elsewhere. (J:181782)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Aicda (mouse)
Summary of all recombinase alleles driven by Aicda.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aicda Mutation:  57 strains or lines available
References
Original:  J:181782 Xu S, et al., The RNase III enzyme Dicer is essential for germinal center B-cell formation. Blood. 2012 Jan 19;119(3):767-76
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory