Gene Expression Data
Assay Details
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Assay
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Reference:
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J:85926
Goodyear RJ, et al., A receptor-like inositol lipid phosphatase is required for the maturation of developing cochlear hair bundles. J Neurosci. 2003 Oct 8;23(27):9208-19
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5315553
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Gene symbol:
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Ptprq
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Gene name:
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protein tyrosine phosphatase receptor type Q
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Antibody:
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anti-Ptprq
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Detection system:
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Secondary antibody coupled to fluorescein
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Assay notes:
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Fixative was 3.7% formaldehyde/0.025% glutaraldehyde. The authors did not specify which antibody was used, anti-Ptprq2 (MGI:5315550) may have been used as well.
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Results
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Specimen
2a:
postnatal day 2
(more  )
Specimen
2a:
(close  )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cochlea |
Present |
Regionally restricted |
2a
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Expression is on hair bundles.
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Specimen
2b:
postnatal day 15
(more )
Specimen
2b:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 15
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: saccule |
Present |
Regionally restricted |
2b
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Expression is on hair bundles.
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Specimen
2c:
postnatal day 21
(more )
Specimen
2c:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 21
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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Specimen
3a:
postnatal day 2
(more )
Specimen
3a:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cochlea |
Present |
Regionally restricted |
3a
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Specimen
3b:
postnatal day 21
(more )
Specimen
3b:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 21
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: crista ampullaris |
Present |
Regionally restricted |
3b
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Expression is on inner hair cells where staining is concentrated at the proximal end of the hair bundle.
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Specimen
3c:
postnatal day 21
(more )
Specimen
3c:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 21
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: macula of utricle |
Present |
Regionally restricted |
3c
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Expression is at the proximal end of the hair bundle in the striolar regions of the utricular macula.
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Specimen
3d:
postnatal day 15
(more )
Specimen
3d:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 15
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: crista ampullaris |
Present |
Regionally restricted |
3d
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Expression is at the proximal end of the hair bundle at the apex of the crista, at peripheral region of the crista the hair bundle is stained up to its tip.
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Specimen
5a':
embryonic day 13.5
(more )
Specimen
5a':
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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Specimen
5b':
embryonic day 18.5
(more )
Specimen
5b':
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: cochlea |
Present |
Regionally restricted |
5b'
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Expression is on inner and outer hair cells in the base of the cochlea.
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Specimen
5c':
postnatal day 2
(more )
Specimen
5c':
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cochlea |
Strong |
Regionally restricted |
5c'
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Expression is on basal-coil outer hair cells.
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Specimen
5d':
postnatal day 21
(more )
Specimen
5d':
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 21
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlea |
Present |
Regionally restricted |
5d'
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Expression is on inner hair cells and absent on basal-coil outer hair cells.
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Specimen
5e':
postnatal day 21
(more )
Specimen
5e':
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 21
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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Specimen
7a:
postnatal day 8
(more )
Specimen
7a:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 8
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlea |
Present |
Regionally restricted |
7a
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Specimen
7b:
postnatal day 8; Ptprqtm1Bow/Ptprq +
(more )
Specimen
7b:
(close )
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Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Ptprqtm1Bow/Ptprq+
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Age:
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postnatal day 8
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlea |
Present |
Regionally restricted |
7b
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Specimen
7c:
(close )
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Genetic Background:
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involves: 129/Sv * C57BL/6
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Mutant Allele(s):
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Ptprqtm1Bow/Ptprqtm1Bow
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Age:
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postnatal day 8
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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Specimen
7d:
postnatal day 67
(more )
Specimen
7d:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 67
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: saccule |
Present |
Regionally restricted |
7d
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Specimen
7e:
postnatal day 67; Ptprqtm2Bow/Ptprq +
(more )
Specimen
7e:
(close )
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Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Ptprqtm2Bow/Ptprq+
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Age:
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postnatal day 67
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: saccule |
Present |
Regionally restricted |
7e
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Specimen
7f:
(close )
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Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Ptprqtm2Bow/Ptprqtm2Bow
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Age:
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postnatal day 67
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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Specimen
Not shown E17.5:
embryonic day 17.5
(more )
Specimen
Not shown E17.5:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: cochlea |
Present |
Regionally restricted |
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Expression is on inner hair cells in the basal coil of the cochlea.
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Specimen
Not shown P M 6:
postnatal month 6
(more )
Specimen
Not shown P M 6:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlea |
Strong |
Regionally restricted |
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Expression is on the hair bundles of inner hair cells and apical-coil outer hair cells.
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| TS28: inner ear vestibular component |
Strong |
Regionally restricted |
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Expression is on the hair bundles.
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