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Sema3dtm2.1(GFP/cre)Joe
Targeted Allele Detail
Summary
Symbol: Sema3dtm2.1(GFP/cre)Joe
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; targeted mutation 2.1, Jonthan Epstein
MGI ID: MGI:5317896
Synonyms: Sema3DGFPcre, Sema3dtm1.1(GFP/cre)Cjt
Gene: Sema3d  Location: Chr5:12433352-12638915 bp, + strand  Genetic Position: Chr5, 3.97 cM, cytoband A2
Alliance: Sema3dtm2.1(GFP/cre)Joe page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:183083
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Sema3dtm2.1(GFP/cre)Joe expression driven by 1 gene
 
Mutation details: An eGFP/cre fusion gene and an Frt-flanked neo cassette was inserted into the Sema3d locus at the ATG codon, replacing the remaining exon 2 sequence by homologous recombination in TL-1 ES cells. The neo was deleted by crossing germline mutants to Flp-expressing mice. (J:183083)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sema3d (mouse)
Summary of all recombinase alleles driven by Sema3d.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 22 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sema3d Mutation:  53 strains or lines available
References
Original:  J:183083 Katz TC, et al., Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cells. Dev Cell. 2012 Mar 13;22(3):639-50
All:  7 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory