Tg(LPV-cre)607Roho
Transgene Detail
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| Symbol: |
Tg(LPV-cre)607Roho |
| Name: |
transgene insertion 607, Rodney JY Ho |
| MGI ID: |
MGI:5319171 |
| Synonyms: |
LPV-Cre.0607 |
| Transgene: |
Tg(LPV-cre)607Roho Location: unknown
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| Alliance: |
Tg(LPV-cre)607Roho page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(LPV-cre)607Roho expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| virus |
LPV |
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Mutation details: The transgenic construct contained the lymphotropic papovavirus (LPV) control region followed by an intron-nls cre-polyA sequence. This fragment was microinjected into fertilized pronuclei and four founders were generated, Two founders (0605 and 0607) transmitted the transgene to F1 offspring. Line 607 animals were crossed to Z/EG reporter mice and EGFP protein and mRNA were analyzed. EGFP expression was detected only in the brain and only the choroid plexus epithelium was positive for EGFP protein with no overlap with GFAP detection, indicating no expression in astrocytes. This line carries four copies of the transgene.
(J:183582)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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LPV
(virus)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:183582 Crouthamel MH, et al., Development and characterization of transgenic mouse models for conditional gene knockout in the blood-brain and blood-CSF barriers. Transgenic Res. 2012 Feb;21(1):113-30 |
| All: |
1 reference(s) |
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Analysis Tools
