Tmem106btm2a(KOMP)Wtsi
Targeted Allele Detail
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| Symbol: |
Tmem106btm2a(KOMP)Wtsi |
| Name: |
transmembrane protein 106B; targeted mutation 2a, Wellcome Trust Sanger Institute |
| MGI ID: |
MGI:5319917 |
| Synonyms: |
TMEM106Bt |
| Gene: |
Tmem106b Location: Chr6:13069758-13089268 bp, + strand Genetic Position: Chr6, 5.38 cM, cytoband A2
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| Alliance: |
Tmem106btm2a(KOMP)Wtsi page
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| IMPC: |
Tmem106b gene page |
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| Mutant Cell Line: |
EPD0047_1_E02 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:250046
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| Parent Cell Line: |
JM8.F6 (ES Cell)
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| Strain of Origin: |
C57BL/6N
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| Project Collection: |
KOMP-CSD
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| Allele Type: |
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Targeted (Conditional ready, Hypomorph, Reporter) |
| Mutation: |
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Insertion
Vector: L1L2_gt1
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Mutation details: The L1L2_gt1 cassette was inserted at position 13074587 of Chromosome 6 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 13075361. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:148605, J:173534, J:311484)
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| Original: |
J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009; |
| All: |
15 reference(s) |
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Analysis Tools
