Gt(ROSA)26Sortm6(Acta2-cre)Npa
Targeted Allele Detail
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| Symbol: |
Gt(ROSA)26Sortm6(Acta2-cre)Npa |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 6, Novartis Pharma AG |
| MGI ID: |
MGI:5424002 |
| Synonyms: |
mR26-alphaSMA-Cre |
| Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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| Alliance: |
Gt(ROSA)26Sortm6(Acta2-cre)Npa page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:184312
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| Parent Cell Line: |
BALB/c-I (ES Cell)
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| Strain of Origin: |
BALB/cJ
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| Allele Type: |
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Targeted (RMCE-ready, Recombinase) |
| Mutation: |
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Insertion
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Gt(ROSA)26Sortm6(Acta2-cre)Npa expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Acta2 |
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Mutation details: Recombinase-mediated cassette exchange (RMCE) replaced the floxed hygro cassette in Gt(ROSA)26Sortm5Npa with an FRT3 site, Acta2 promoter, cre, neo cassette and FRT site.
(J:184312)
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Generation of the Gt(ROSA)26Sortm7(Cdh5-cre)Npa and Gt(ROSA)26Sortm6(Acta2-cre)Npa alleles |
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Acta2
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gt(ROSA)26Sor Mutation: |
993 strains or lines available
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| Original: |
J:184312 Tchorz JS, et al., A modified RMCE-compatible Rosa26 locus for the expression of transgenes from exogenous promoters. PLoS One. 2012;7(1):e30011 |
| All: |
1 reference(s) |
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Analysis Tools
